Transformation of dermatofibrosarcoma protuberans into a fibrosarcoma

Dermatofibrosarcoma protuberans with fibrosarcomatous transformation*

To the Editor, Dermatofibrosarcoma protuberans (DFSP) is an uncommon sarcoma of the skin and soft tissue with an intermediate level of malignancy. DFSP with fibrosarcomatous differentiation (FS-DFSP) is a rare variant of DFSP, involving greater aggression, higher rates of local recurrences and a higher metastatic potential. We describe the case of a 70-year-old woman who presented with a painle...

Dermatofibrosarcoma protuberans.

Overview The NCCN Non-Melanoma Skin Cancer Panel has developed these guidelines outlining the treatment of dermatofibrosarcoma protuberans (DFSP) to supplement their other guidelines (NCCN Clinical Practice Guidelines in Oncology [NCCN Guidelines] for Basal Cell and Squamous Cell Skin Cancers and Merkel Cell Carcinoma; to view the most recent version of these guidelines, visit the NCCN Web site...

Dermatofibrosarcoma protuberans with fibrosarcomatous transformation of the head and neck

Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous neoplasm associated with a high cure rate. We present a case of aggressive DFSP with fibrosarcomatous areas in the head and neck. A 28-year-old Mediterranean female presented with a 45-day history of rapidly growing cutaneous lesion of the face. Surgical biopsy confirmed the diagnosis of DFSP. Subsequently, the patient underwent wide lo...

Dermatofibrosarcoma Protuberans in Childhood

Dermatofibrosarcoma protuberans in childhood.

Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous tumor with a possibly misleading presentation. It is rare in childhood. We report an 18-month-old child with an acquired atrophic plaque of the left ankle. Based on clinical findings, initial proposed diagnoses included localized scleroderma and localized lipoatrophy. At the age of 5 years the plaque had increased in size and become a p...